Stage 01

Tingling Stage

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Tingling, discomfort, itching.
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The area becomes red & swollen due to the inflammatory reaction.
Stage 02

Blistering Stage

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White blood cells travel to the blister to help fight the infection.
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The cold sore blister fills with fluid that contains viral particles.
Stage 03

Weeping (Ulcer)
Stage

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This may be the most painful stage of your outbreak.
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The blisters burst and a shallow ulcer (open sore) develops.
Stage 04

Crusting and
Scabbing Stage

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The cold sore dries out and a golden-brown crust appears.
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The scab shrinks & cracks can bleed.
Stage 05

Healing Stage

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Your scab starts to fall off.

Fenivir® is effective at any stage of cold sores.
Fenivir® (penciclovir) is superior to acyclovir7 and should be preferred as topical treatment6